Perfusion Medical is commercializing PEG-20k, a breakthrough IV solution for restoration of tissue perfusion invented at the Virginia Commonwealth University (VCU) School of Medicine. PEG-20k shows potential to be a disruptive solution for addressing severe blood loss (hemorrhagic shock) and related medical conditions.Learn More
How it works
The major mechanism of action of PEG-20k IV solution in treating severe hypovolemic shock is to increase tissue perfusion to facilitate rapid transfer of oxygen into oxygen starved tissues and organs. This is accomplished by reversing the metabolic cell and tissue swelling that occurs during shock, which causes no reflow by capillary compression.
Perfusion Medical is commercializing a critical new life science technology
See our Technology and Pipeline page to learn more about how PEG-20k works and how it can potentially help patients
See our Press page to see a list of some of the impressive scientific publications about PEG-20k
Read our blogs to learn more about the Perfusion Medical team and where we are in the development, regulatory and investment process
The development of PEG-20k at VCU was funded with more than $10 million from the US Army. PEG-20k has tremendous potential to help war fighters and civilians
Superior Survival Outcomes of a Polyethylene Glycol-20k Based Resuscitation Solution
Annals of Surgery - Superior early and 24-hour outcomes were observed with PEG-20k LVR compared to WB and Hextend in a preclinical porcine model of lethal HS, despite decreased OCC from substantial volume-expansionRead More
Effects of Polyethylene Glycol‐20k on Coronary Perfusion Pressure and Postresuscitation Myocardial.
Journal of the American Heart Association - Aortic infusion of PEG‐20k during cardiopulmonary resuscitation increases coronary perfusion pressure to the same extent as epinephrine, improves postresuscitation myocardial and cerebral function, and increases duration of survival in a rat model of cardiac arrest.Read More
Low-volume resuscitation using polyethylene glycol-20k in a preclinical porcine model…
The Journal of Trauma and Acute Care Surgery - In a preclinical model of controlled hemorrhagic shock, PEG-20k-based LVR solution increased tolerance to the shock state 16-fold compared to saline.Read More